Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Etiology/Pathophysiology:
Highly malignant. Lower extremities are the most frequent site. Most
commonly arises in the metaphysis where the lesions are eccentric,
next most frequently in the diaphysis where the lesions are central
in location. Late metastases are characteristic, particularly to
other bones.
Pathology:
Not applicable
Imaging Findings:
Usually purely lytic, may be lytic with a periosteal reaction, rarely
are sclerotic. The bone destruction is usually permeative in
appearance and the periosteal new bone has an onion skin appearance.
DDX:
References:
See related Provider Topics Bone Cancer, Bones, Joints and Muscles or Cancers.
See related Patient Topics Bones, Joints and Muscles or Cancers.
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