Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Etiology/Pathophysiology:
Etiology unknown. Due to abnormal proliferation of histiocytes
throughout the reticuloendothelial system. Any organ system may be
involved. This is the acute disseminated form involving the bone
marrow, lymphatics, and solid organs. There may be no skeletal
lesions. Prognosis is poor.
Pathology:
See abnormal proliferation of histiocytes throughout the
reticuloendothelial system.
Imaging Findings:
May have generalized osteopenia with decreased cortical thickness if
the disease is in a disseminated form.
DDX:
References:
See References Chapter.
See related Provider Topics Bone Cancer, Bones, Joints and Muscles or Cancers.
See related Patient Topics Bones, Joints and Muscles or Cancers.
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