Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Etiology/Pathophysiology:
Due to abnormal formation of osteoid, matrix, and collagen associated
with osteoblastic dysfunction. Usually lethal and the patients die
due to pulmonary insufficiency. Often autosomal recessive, frequently
a spontaneous mutation that manifests at birth.
Pathology:
Not applicable
Imaging Findings:
Multiple fractures of various ages.
DDX:
References:
See References Chapter.
See related Provider Topics Bones, Joints and Muscles, Genetics/Birth Defects or Osteogenesis Imperfecta.
See related Patient Topics Bones, Joints and Muscles or Genetics/Birth Defects.
Virtual Children's Hospital Home | Virtual Hospital Home | Site Map | Mirror Sites | Search
Provider Health Topics A-Z | Provider Textbooks | Patient Health Topics A-Z | Patient Textbooks
About Us | Continuing Education | Translations | Links | Support Us
Policies | Comments and Questions | E-mail This Page | UI Health Care Home
All contents copyright © 1992-2004 the Author(s) and The University of Iowa. All rights reserved.
http://www.vh.org/pediatric/provider/radiology/PAP/MSDiseases/OsteogenImpCongenita.html